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Suite 3B equipment schedule

CMP-26-101 active conflict

Batches, CIP/SIP windows and equipment availability across the upstream and harvest skids. Built from the Maximo PM schedule and the MES planning extract; SAP ERP is not connected.

Schedule as of 06:45 UTCTimes UTCDemo · read-only
Inspect affected pump PM-204Submit shift proposal
Frame PLAN-01
Batch / processCIP / SIPPreparationEquipment requiredUnavailableCollision
Preview
BR-UP-012,000 L fed-batch bioreactorPM-204Masterflex feed pumpPM-205Standby feed pumpCE-01Disc-stack centrifugeUF-DF-02UF/DF skidCIPCIP skid (shared)Mon 19 Oct061218Tue 20061218Wed 21061218Thu 22061218Fri 23061218Sat 24061218Sun 25061218Mon 26061218Tue 27061218MES-26073 fed-batch end & harvest · 0.0–92.0 h · QA hold active on lotMES-26073 fed-batch end & harvestCIP/SIP BR-UP-01 · 104.0–116.0 hCIP/SIP…Media fill & equilibration · 152.0–177.5 hMedia fill & equi…MES-26074 inoculation → culture · 177.5–216.0 hMES-26074 inoculation → cul…Feed MES-26073 · 0.0–80.0 hFeed MES-26073PM-SAN-204 sanitization · 174.0–182.0 h · Maximo PM-SAN-204-W44Required for MES-26074 · 177.5–216.0 hRequired for MES-26074Standby · OQ overdue · no tubing installed · 0.0–216.0 hStandby · OQ overdue · no tubing installedClarify MES-26073 · 92.0–100.0 hCIP · 100.0–104.0 hUF/DF MES-26073 · 106.0–118.0 hUF/DF M…CIP · 118.0–122.0 hCE-01 · 100.0–104.0 hBR-UP-01 · 104.0–116.0 hBR-UP-0…UF-DF-02 · 118.0–122.0 hPM-204 · 174.0–182.0 hOverlap 4.5 hOverlap 4.5 hnow

Click any bar for details. Previews are local to this browser; the schedule of record in MES/Maximo is unchanged.

Constraint resolver sandbox

Two drafted options. Select one to preview it above. Neither is applied; a proposal needs supervisor and QA review.

Proposal

Scenario A

Shift MES-26074 inoculation +4.5 h

  • ConflictCalculated

    Removed · inoculation starts after PM-SAN-204 ends (Mon 26 Oct 14:00)

  • MES-26074 timelineCalculated

    All downstream steps +4.5 h; harvest moves to Mon 9 Nov 14:00

  • Media hold in vesselUnknown

    25.5 h → 30.0 h. Validated hold limit not found in connected sources

  • StaffingObservation

    Inoculation lands at shift handover (14:00); supervisor confirmation needed

  • QualificationObservation

    No equipment substitution; no qualification impact

Scenario B

Divert MES-26074 feed to standby PM-205

  • ConflictCalculated

    Removed · MES-26074 uses PM-205; inoculation time unchanged

  • QualificationObservation

    PM-205 OQ overdue by 17 d · requires OQ re-execution or QA-approved justification

  • PreparationCalculated

    Tubing install + dynamic slip verification (SOP-UP-014 §7.2) ≈ 6 h before inoculation

  • Batch recordObservation

    Equipment substitution in eBR needs QA approval before execution

  • Pump historyUnknown

    PM-205 has no feed-delivery history on this process

PM-205 qualification status:

Scenario A has fewer qualification dependencies; Scenario B keeps the timeline. The trade-off is a supervisor and QA decision.

Submit shift proposal

Equipment availability

Next 7 days

BR-UP-01BookedMES-26073 → MES-26074
PM-204ConflictSanitization vs inoculation
PM-205Not readyOQ overdue · no tubing
CE-01AvailableAfter Fri 23 08:00
UF-DF-02AvailableAfter Sat 24 02:00
CIP skidAvailable4 bookings, no overlap

Data coverage

ObservationPM and CIP windows from Maximo.

UnknownOperator rosters and SAP ERP material availability are not connected, so staffing and material constraints are not checked.

Inspect affected pump PM-204