Background agents

Writeback locked · read-only

Agents run in the background within explicit permissions. They read from systems of record and produce drafts or proposals; nothing they produce takes effect without a named person’s signature.

Mesa Site (UP-01)Agent policy v4 · approved by P. Natarajan 2026-09-30

Inspect run RUN-2026-1042

Configured roles

8 active · 1 paused

In-flight tasks

Running now

Awaiting review

Drafts and proposals

DCS writeback

LOCKED_READ_ONLY

Not configurable in UI

Platform safety boundary

All connectors use read-only service accounts; no write paths to MES, DCS/PLC, LIMS, QMS or ERP.
Agent outputs are drafts or proposals, stored separately from source records.
Every proposal names its required human approvers; approval is recorded with e-signature meaning.
Each run logs tool versions, inputs and outputs to the audit trail. Governance settings

Agent roles

Data Intake

Pull, align and quality-check records from connected systems for a workspace.

Running

Trigger: New batch phase, connector sync, or a user request
Reads: OSIsoft PIDeltaV eBRLabWare LIMSread-only
May produce: Aligned dataset drafts with gap and unit reports
Human gate: MSAT Lead confirms mappings
Owner: Alex Rivera

Resolving 3 of 8 sources for MES-26073 Phase 05 refresh

MSAT Yield Sentry

Watch campaign yield and CPP trends; open an investigation draft when a batch falls outside its envelope.

Awaiting review · 1

Trigger: Yield index < target − 3 pts or CPP alarm on a campaign batch
Reads: OSIsoft PIDeltaV eBRMaximo CMMSLabWare LIMSread-only
May produce: Investigation trace and recipe patch proposal
Human gate: MSAT Lead + QA Reviewer sign in REV-01
Owner: Alex Rivera

RUN-2026-1042 stopped at human checkpoint

Open

Tech Transfer Link

Compare donor and recipient process parameters and flag unmapped items.

Idle

Trigger: Tech transfer gate review scheduled
Reads: DocumentumDeltaV eBRread-only
May produce: Parameter gap list for TT-006
Human gate: Transfer lead reviews gap list
Owner: Alex Rivera

Last run 2 days ago · TT-006 Gate 2 gap list

Open

Deviation Narrative Drafter

Draft deviation descriptions and timelines from cited records.

Awaiting review · 2

Trigger: Deviation opened in Veeva Vault QMS
Reads: Veeva Vault QMSDeltaV eBROSIsoft PIread-only
May produce: Narrative and timeline drafts (never filed automatically)
Human gate: QA Reviewer edits and files in QMS
Owner: Priya Natarajan

2 narrative drafts for Q-DEV-031

Open

Lab Result Watcher

Flag out-of-trend LIMS results against campaign history.

Idle

Trigger: New LIMS result on an active batch
Reads: LabWare LIMSread-only
May produce: OOT notifications with trend context
Human gate: Analyst and QA review in LIMS
Owner: Priya Natarajan

Last event QC-948 OOT at 11:40 UTC

Open

Maintenance Correlator

Link equipment alarms to recent work orders and calibration records.

Running

Trigger: Equipment alarm or work order closed on a GMP asset
Reads: Maximo CMMSOSIsoft PIread-only
May produce: Correlation notes on equipment records
Human gate: Maintenance planner reviews
Owner: Marcus Bell

Correlating ALM-UP-204 with PM-204 history

Open

Schedule Conflict Checker

Detect equipment and resource overlaps in the MES schedule.

Awaiting review · 1

Trigger: MES schedule export changes
Reads: DeltaV eBRMaximo CMMSread-only
May produce: Conflict reports and resolution scenarios
Human gate: Cleanroom Supervisor chooses a scenario
Owner: Marcus Bell

CIP-UP01-118 overlaps MES-26074 by 4.5 h

Open

Knowledge Indexer

Keep the search index current with effective document versions and permissions.

Idle

Trigger: Nightly, or on document effective-date change
Reads: DocumentumVeeva Vault QMSMaximo CMMSDeltaV eBRLabWare LIMSread-only
May produce: Search index entries (no document edits)
Human gate: None needed — index only; permissions inherited
Owner: IT · R. Osei

Index refreshed 08:40 UTC · 41,208 records

Open

Audit Packager

Assemble evidence and audit-trail packages for a decision or record.

Paused

Trigger: Review approved or on request
Reads: Platform audit logread-only
May produce: Audit package drafts with hash manifest
Human gate: QA Reviewer releases package
Owner: Priya Natarajan

Paused by P. Natarajan pending template update

Open

Event stream

Kafka transport · topic mos.events.up01 · read-only consumers

Simulated

Live (simulated)15 events / tick

What agents cannot do

Change setpoints, recipes or equipment states.
File, approve or close records in QMS or LIMS.
Read data outside the requesting user’s permissions.
Mark their own proposals as approved or effective.

Execution ledger

Recent runs across all agents · every row links to its audit trail entry

Run	Agent	Trigger	Duration	Data scope (read)	Outcome	Reviewer
RUN-2026-1042	MSAT Yield Sentry	ALM-UP-204 + yield < target	6m 41s	PI, eBR, CMMS, LIMS	Awaiting human authorization	A. Rivera, P. Natarajan
RUN-2026-1041	Lab Result Watcher	QC-948 result posted	0m 38s	LIMS	Notification sent	M. Okafor
RUN-2026-1040	Deviation Narrative Drafter	Q-DEV-031 opened	2m 12s	QMS, eBR, PI	Draft awaiting review	P. Natarajan
RUN-2026-1039	Schedule Conflict Checker	MES schedule export	1m 05s	eBR, CMMS	Draft awaiting review	M. Bell
RUN-2026-1038	Data Intake	PI connector resync	4m 50s	PI	Completed with gap (42 min)	A. Rivera
RUN-2026-1037	Audit Packager	Manual request	0m 21s	Audit log	Failed: template v3 missing	—
RUN-2026-1036	Knowledge Indexer	Nightly 02:00	18m 02s	5 systems	Completed	Not required

Agent roles

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